PIXUL for Proteomics Core Facilities: One Instrument for Your Whole Sample Range
A shared core is judged on how many groups it can serve. PIXUL preps your whole sample range — the tough samples included — in one walk-away run instead of one sample at a time.
This two-page reference walks through PIXUL's three-step acoustic workflow — load, program, sonicate — for a shared proteomics core. It lays out the all-in-one advantage over probe and focused-ultrasonication sample prep, then presents a head-to-head showing equivalent peptide and protein recovery against a probe sonicator at 96-sample scale.
Read or download to see:
- Your whole sample range in one walk-away run — cultured cells, tissue, bacteria, yeast, and FFPE prep on a single instrument instead of a separate one for each, with tough samples like plant and heart or muscle tissue included by adjusting the run time.
- Up to 96 samples in one run on standard 96-well plates — arrayed piezoelectric transducers process the whole plate in one walk-away run, column by column rather than one sample at a time. Up to 12 column-level programs (one per column) let mixed sample types prep together in the same plate, with no proprietary consumables.
- All-in-one, unlike probe and focused-ultrasonication prep — probes run one sample at a time, and focused ultrasonication needs proprietary consumables plus an external chiller and separate computer. PIXUL puts integrated chilling, a built-in touchscreen, and a self-contained benchtop into one walk-away instrument.
- Matched probe sonication, head to head — equivalent peptide and protein recovery from HEK cells and mouse tissue, prepped on PIXUL versus a probe sonicator into the same LC-MS/MS workflow, so protein-ID depth is set by your mass spec, not the lysis step.
