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A practical guide to choosing a cell disruption and protein extraction instrument for a proteomics core facility

The instrument that disrupts cells and extracts protein sits at the front of every workflow your core runs — this guide shows how to choose it on the range it handles and the uptime it promises, not one tidy benchmark.

What You'll See Inside

Six criteria

The six things that actually decide the choice, ordered how cores weigh them.

Ask + test

For each: the question to ask and the one thing to test before you commit.

Shared-resource lens

Why one tidy benchmark is the wrong measure for a facility serving many groups.

Scoring worksheet

A worksheet to score your current setup, or any candidate, against all six.

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